For example, make sure that
$ export PYTHON_IRODSCLIENT_CONFIG__GENQUERY1__IRODS_QUERY_LIMIT=128
$ python -ic 'import irods.query; print (irods.query.IRODS_QUERY_LIMIT ==
irods.client_configuration.genquery1.irods_query_limit ==
128)'
produces an output of True.
Only, it might be advisable to make the tests even more general than that.